Artificial Blood Has Long-Bedeviled Scientists, But Breakthrough May Be On The Horizon
The artificial blood could be freeze-dried and stored safely for years. In other public health news: antibiotic-resistant infections, aid in dying, gene editing, alcoholism, obesity and more.
Stat:
Artificial Blood: The Quest For One Of Science's Holy Grails
The need for such a product is clear. Blood loss from traumatic injuries is responsible for thousands of deaths annually, and even when people survive, oxygen depletion can leave tissue permanently injured. Fresh blood can only be stored for 42 days, and only lasts for a few hours unrefrigerated. A substitute could be vital in settings like battlefields or rural areas without easy access to blood, used as a stopgap measure to keep the injured alive until they get to a hospital. But the quest to develop substitute blood has bedeviled researchers in academia, the military, and the biopharma industry, with several companies — including Baxter, Northfield Laboratories, and Biopure — abandoning their attempts. (Joseph, 2/27)
The Washington Post:
Dangerous Antibiotic-Resistant Infections On The Rise For Children In The U.S., Study Finds
Rising infections caused by a type of bacteria resistant to multiple antibiotics is causing longer hospitalizations and may mean a higher risk of death for children in the United States, according to a new study. The study, published this week in the Journal of the Pediatric Infectious Diseases Society, found that 3 out of 5 children admitted to hospitals already had an antibiotic-resistant infection — suggesting these infections are spreading more often in the community. (Naqvi, 2/25)
The New York Times:
Gorsuch Staunchly Opposes ‘Aid In Dying.’ Does It Matter?
Ever since President Trump nominated Judge Neil M. Gorsuch to fill the empty seat on the Supreme Court, interested parties have been combing through his writings and appellate court rulings looking for signs and portents. If he’s confirmed, how might Judge Gorsuch vote on affirmative action questions? Or challenges to Roe v. Wade? But nobody has to do much head-scratching over his position on medical aid in dying. (Span, 2/24)
The Wall Street Journal:
DIY Gene Editing: Fast, Cheap—And Worrisome
Kian Sadeghi has postponed homework assignments, sports practice and all the other demands of being a 17-year-old high-school junior for today. On a Saturday afternoon, he is in a lab learning how to use Crispr-Cas9, a gene-editing technique that has electrified scientists around the world—and sparked a widespread debate about its use. Scientific breakthroughs often raise big ethical questions. Moral concerns around the 1996 cloning of Dolly the sheep or the 2000 announcement of a rough draft of the human genome still reverberate today. The public benefits from scientific advances, particularly in improving health. But some scientists say the power to alter the DNA of plants, animals or people, and the profound impact such changes may have on individuals and society, merits public discussion. (Marcus, 2/26)
NPR:
A Medicine That Blunts Opioids Can Help Problem Drinkers, Too
If you drink more alcohol than you want to or should, you're not alone. A nationwide survey by the National Institutes of Health found that 28 percent of adults in the U.S. are heavy drinkers or drink more than is recommended.Yet, most heavy drinkers don't get the help they need. "The biggest problem we have in the field is that less than 10 percent of individuals with an alcohol use disorder get any treatment whatsoever," says George Koob, director of the National Institute on Alcohol Abuse and Alcoholism. (Aubrey, 2/27)
Boston Globe:
Violence As A Disease: Hospitals Treat Wounds, Physical And Otherwise
The victim’s arrival signals that more violence is likely to occur, and opens an opportunity to heal the social and emotional maladies that feed violence. As many as 45 percent of people who go to the hospital with violent injuries return within five years, shot or stabbed again, sometimes fatally. And retaliation can lead to further shootings. (Freyer, 2/27)
NPR:
Patients Speak Up To Improve Medical Science — And Their Own Care
Many studies designed to try out new drugs simply languish. They don't attract enough patients, and they aren't completed. That slows medical progress. But here's a story of one study that has bucked that trend — in fact, it is so popular, scientists had to put the brakes on it for a while. The study is called the NCI-MATCH trial. It upends the normal way of classifying cancers for treatment: Instead of categorizing malignancies by the organ where they first appear, this method of sorting focuses on particular mutations in the genes of cancer cells. (Harris, 2/24)
The New York Times:
Doctors Consider A Last Best Hope For Obese Teenagers: Surgery
If all goes well, Aliayha Carrasco-Garcia will have an operation next month that will change her life. She will shed many of the 240 pounds that now burden her 5-foot-2 frame. Like many who have bariatric surgery, she has tried diets and exercise to no avail. Surgery is her last best hope. But there is a difference between Aliayha and almost everyone else who has had this operation: She is only 15. (Kolata, 2/24)
Stateline:
Should People Be Barred From Buying Junk Food With Food Stamps?
Twenty-three cents of every food stamp dollar is used to buy candy, desserts, salty snacks, sugar and sweetened beverages, according to a November report from the U.S. Department of Agriculture that for the first time revealed purchasing habits under the program in detail. The report, along with the election of President Donald Trump, who may be more inclined to tighten welfare rules, has reignited a long-standing debate on whether the government should allow people to use food stamps to buy unhealthy food. Lawmakers in at least five states — Arkansas, Florida, Mississippi, New Mexico and Tennessee — introduced bills this year to ask the USDA for permission to ban the purchase of certain kinds of food or drinks, such as candy and soda, with food stamps. Since the USDA administers the program, states can’t create their own restrictions. But the department can give a state permission to conduct a pilot to test new ideas — something it has so far been unwilling to do. (Fifield, 2/24)
Boston Globe:
Startups’ Latest Nut To Crack: Food Allergies
As more Americans are diagnosed with food allergies — as many as 15 million and counting — there’s a growing consensus that the research has not kept pace. In November, the National Academies of Sciences released a damning report warning that “insufficient or inconsistent data and studies” have left the allergic casting about for answers. (Nanos, 2/26)
San Francisco Chronicle:
Science Closing In On Polio-Like Virus That Paralyzed Children
Scientists are closer than ever to proving that new strains of an old virus are to blame for recent waves of polio-like paralysis in children that have stumped doctors and alarmed parents across the country. Laboratory mice exposed to the virus, called Enterovirus D68, often developed sudden-onset paralysis in one or more limbs a few days later, according to research published last week by a team of scientists from UCSF, the University of Colorado School of Medicine and the California Department of Public Health. (Allday, 2/26)
Miami Herald:
New Study Reveals LGBT Seniors Have Higher Health Risks But Are Also Very Resilient
A series of reports believed to comprise the first longitudinal study of its kind found that LGBT Americans aged 50 and older are at a higher risk of disability, cardiovascular disease, depression and social isolation. But the group — at 2.7 million strong — is also resilient, choosing to be active in the community, participate in wellness activities and serve in the military. (Veciana-Suarez, 2/24)
The Associated Press:
Pediatricians Warn Against Pot Use: Not Your Dad’s Marijuana
An influential doctors group is beefing up warnings about marijuana’s potential harms for teens amid increasingly lax laws and attitudes on pot use. Many parents use the drug and think it’s OK for their kids, but “we would rather not mess around with the developing brain,” said Dr. Seth Ammerman. (Tanner, 2/27)
KQED:
White House Spokesman Predicts More Federal Action Against Marijuana
The Justice Department may step up enforcement of federal marijuana laws in states that have voted to legalize its recreational use, according to White House press secretary Sean Spicer. (Rott, 2/24)