As Superbug Threat Looms, Scientists Discover New Antibiotic In Human Nose
The new antibiotic can kill MRSA, the poster child for drug resistance and the culprit behind the most pernicious hospital-acquired staph infections.
The Washington Post:
Scientists Find New Antibiotic In The Human Nose
Scientists have discovered a bacterium living inside the human nose that produces an antibiotic capable of killing one of the most hard-to-treat pathogens — a pathogen that causes serious, even deadly skin and wound infections, bloodstream infections and pneumonia. German researchers found that this antibacterial substance was effective in treating skin infections in mice caused by Staphylococcus aureus bacteria, according to a study published Wednesday in Nature. The scientists said the substance, which they named lugdunin, has potent antimicrobial effects against a wide range of bacteria, including antibiotic-resistant strains such as methicillin-resistant S. aureus (MRSA) and vancomycin-resistant Enterococcus bacteria. (Sun, 7/27)
NPR:
'Nose-y' Bacteria Could Yield A New Way To Fight Infection
The scientists already knew that S. aureus lives in the noses of about 30 percent of humans, usually without causing harm — most people never know they are carriers of the bacterium. But if the body becomes compromised (whether by surgery, physical trauma, an underlying illness or suppressed immune system) the little cache of S. aureus in the nose can suddenly launch an attack against its human host. And if the strain of bacteria is MRSA, that infection can be lethal. (Beans, 7/27)
Stat:
This Smells Promising: Nasal Bacteria Pump Out A New Antibiotic That Kills MRSA
“Our study can help to understand what we can do to eradicate these pathogens from the microbiota of healthy people,” said Andreas Peschel, lead author of the study, published Wednesday in Nature. (Vlasits, 7/27)