Though Predicting Alzheimer’s Remains A Daunting Task, Researchers Take Another Small Step
Scientists have developed a genetic test that can help identify people who are at unusually high risk of developing symptoms of dementia as they age. The test only underlies how complex truly predicting someone's risk for Alzheimer's is, but it's “an important first attempt," experts say. In other news, biotech executives are bringing back the practice of self-experimentation, researchers find that adults cannot regrow cartilage and patients are taking calculated risks with medical marijuana.
Los Angeles Times:
Researchers Develop Genetic Test That Can Predict Your Risk Of Alzheimer's Disease
New research into the genetic underpinnings of Alzheimer’s disease offers fresh evidence that the devastating brain disorder may gain a foothold years before dementia sets in, and takes a key step toward earlier detection of the disease. In a study that scoured the genes of healthy young people for the presence of variants linked to Alzheimer’s disease, researchers have found that those who carried many of the telltale gene variations had a smaller hippocampus -- a brain structure that is crucial to memory-formation – than did their peers with few of the genetic variations. (Healy, 7/6)
Stat:
Biotech Execs In Search Of Human Guinea Pigs Find Eager Subjects: Themselves
Such experiments are one of medicine’s oldest traditions. Many a vaccine or poison was first tested on its developer; most of the earliest work on psychedelic drugs was conducted by intrepid scientists tripping in the name of research. As medicine has progressed, however, self-experimentation has become less popular in academic labs, to be taken up instead by a growing biotech industry. Those changes have given rise to a new breed of self-tester: the guinea pig CEO. (Preston, 7/7)
Stat:
Bad News For Creaky Knees: We Can't Regrow Cartilage As Adults, Study Finds
The fallout from nuclear bomb testing decades ago is now helping researchers better understand knee joints. By tracking radioactive carbon absorbed in knees, a team of Danish researchers has found that the structure of cartilage is determined by early adolescence and doesn’t change later in life. They published their findings Wednesday in Science Translational Medicine. (Wessel, 7/6)
PBS Newshour:
Until Research Unlocks Medical Understanding Of Marijuana, Patients Experiment
Lenny and Amy’s 5-year-old son has epilepsy. When conventional medications caused terrible side effects, they started giving him a daily drop of cannabis oil, with dramatic results. But it’s a calculated risk: While there is anecdotal evidence of cannabis’ effectiveness, scientists face research roadblocks because it’s a schedule 1 controlled substance. (O'Brien, 7/6)